UNC13D / Unconjugated / EPR4914

Product Details
Description UNC13D Antibody (Internal, clone EPR4914) IHC-plus‚Ñ¢
Conjugate Unconjugated
Clone EPR4914
Target Species Human, Mouse
Applications FC, IHC-P, ICC, WB, IHC
Supplier LifeSpan
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About UNC13D
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
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