TRPM2 / DyLight 550 /

Product Details
Description This is specific for isoform 1, or the long isoform (TRPM2-L), of TRPM2.
Conjugate DyLight 550
Clone
Target Species Mouse, Rat
Applications ICC, IF, WB, IHC-Fr, IHC
Supplier Novus Biologicals
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Host
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About TRPM2
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016]
About DyLight 550
DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Validation References
PMID 25879940
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