alpha-L-Iduronidase / Unconjugated /
Product Details
| Description | IDUA / MPS1 Antibody (aa121-170) IHC-plus‚Ñ¢ | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Bovine, Equine, Guinea Pig, Hamster, Human, Mouse | |
| Applications | IHC-P, WB, IHC | |
| Supplier | LifeSpan | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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| Price | ||
| Antigen | ||
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About alpha-L-Iduronidase
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008]
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008]
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