Frizzled-8 / Biotin /
Product Details
| Description | FZD8 / Frizzled 8 Antibody (Extracellular Domain, Biotin) IHC-plus‚Ñ¢ | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | ||
| Target Species | Bovine, Canine, Human, Monkey, Mouse, Rabbit, Rat | |
| Applications | IHC-P, IHC | |
| Supplier | LifeSpan | |
| Catalog # | Sign in to view product details, citations, and spectra | |
| Size | ||
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| Antigen | ||
| Host | ||
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About Frizzled-8
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
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