CD161 / PE-eFluor 610 / PK136

Product Details
Description NK1.1 Monoclonal Antibody (PK136), PE-eFluor 610, eBioscience
Conjugate PE-eFluor 610
Clone PK136
Target Species Mouse
Applications FC
Supplier Thermo Fisher Scientific
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About CD161
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
About PE-eFluor 610
PE-eFluor™ 610 (PE-eF610, RPE-eF610) from Thermo Fisher Scientific is an orange-emitting tandem fluorophore that combines pycoerythrin (PE) and eFluor™ 610. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, eF610, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-eF610 has an excitation peak at 565 nm and an emission peak at 607 nm, and is suitable alternative to PE-Texas Red®. PE-eF610 is mainly used for flow cytometry. This tandem is often a great option because of PE is excitable by multiple lasers due to its broad excitation spectrum and the eFluor™ 610 acceptor molecule emits brightly in the Orange/Red spectrum. Many cytometers are commonly set up with the 610/20 bandpass filter that can detect this fluorophore's emission. This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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