IRF-4 / eFluor 660 / 3E4
Product Details
| Description | IRF4 Monoclonal Antibody (3E4), eFluor™ 660, eBioscience™ | |
|---|---|---|
| Conjugate | eFluor 660 | |
| Clone | 3E4 | |
| Target Species | Human, Mouse | |
| Applications | FC | |
| Supplier | Thermo Fisher Scientific | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About IRF-4
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
About eFluor 660
eFluor™ 660 (eF660) from Thermo Fisher Scientific has an excitation peak at 633 nm and an emission peak at 669 nm. It is useful in fluorescence microscopy and flow cytometry applications.
eFluor™ 660 (eF660) from Thermo Fisher Scientific has an excitation peak at 633 nm and an emission peak at 669 nm. It is useful in fluorescence microscopy and flow cytometry applications.
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