CD86 / Unconjugated / PO3.1

Product Details
Description CD86 (B7-2) Monoclonal Antibody (PO3.1), Functional Grade, eBioscienceā„¢
Conjugate Unconjugated
Clone PO3.1
Target Species Mouse
Applications FC, Functional, Block/Neutralize
Supplier Thermo Fisher Scientific
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About CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
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