CD4 / SuperBright 436 / GK1.5
Product Details
Description | CD4 Monoclonal Antibody (GK1.5), Super Bright 436, eBioscience | |
---|---|---|
Conjugate | SuperBright 436 | |
Clone | GK1.5 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Thermo Fisher Scientific | |
Catalog # | Sign in to view product details, citations, and spectra | |
Size | ||
Price | ||
Antigen | ||
Host | ||
Isotype |
About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About SuperBright 436
SuperBright 436 (SB436) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 436 nm. SB436 is spectrally similar to StarBright Violet 440, eFluorâ„¢ 450 and Pacific Blue but can be unmixed with Brilliantâ„¢ Violet 421 on a spectral analyzer. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
SuperBright 436 (SB436) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 436 nm. SB436 is spectrally similar to StarBright Violet 440, eFluorâ„¢ 450 and Pacific Blue but can be unmixed with Brilliantâ„¢ Violet 421 on a spectral analyzer. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
Reviews & Ratings
Reviews |
---|
Looking for more options?
6549 CD4 antibodies from over 61 suppliers available with over 260 conjugates.