CD357 / eFluor 450 / eBioAITR

Product Details
Description CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), eFluor™ 450, eBioscience™
Conjugate eFluor 450
Clone eBioAITR
Target Species Human
Applications FC
Supplier Thermo Fisher Scientific
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About CD357
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
About eFluor 450
eFluor™ 450 (eF450) from Thermo Fisher Scientific has an excitation peak at 405 nm and an emission peak at 450 nm. It is useful in both flow cytometry and fluorescence microscopy.
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