CD357 / SuperBright 600 / DTA-1

Product Details
Description CD357 (AITR/GITR) Monoclonal Antibody (DTA-1), Super Bright 600, eBioscience
Conjugate SuperBright 600
Clone DTA-1
Target Species Mouse
Applications FC
Supplier Thermo Fisher Scientific
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About CD357
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
About SuperBright 600
SuperBright 600 (SB600) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 600 nm. SB600 is spectrally similar to StarBright Violet 610 and BV605. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
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