PD-1 / SuperBright 780 / eBioJ105 (J105)

Product Details
Description CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), Super Brightâ„¢ 780, eBioscienceâ„¢
Conjugate SuperBright 780
Clone eBioJ105 (J105)
Target Species Human, Rhesus
Applications FC
Supplier Thermo Fisher Scientific
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About PD-1
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
About SuperBright 780
SuperBright 780 (SB780) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 780 nm. SB780 is spectrally similar to StarBright Violet 790 and BV785. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
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