PD-1 / eFluor 450 / RMP1-30

Product Details
Description CD279 (PD-1) Monoclonal Antibody (RMP1-30), eFluor™ 450, eBioscience™
Conjugate eFluor 450
Clone RMP1-30
Target Species Mouse
Applications FC
Supplier Thermo Fisher Scientific
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About PD-1
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
About eFluor 450
eFluor™ 450 (eF450) from Thermo Fisher Scientific has an excitation peak at 405 nm and an emission peak at 450 nm. It is useful in both flow cytometry and fluorescence microscopy.
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