CD20 / PE-eFluor 610 / 2H7

Product Details
Description CD20 Monoclonal Antibody (2H7), PE-eFluor 610, eBioscience
Conjugate PE-eFluor 610
Clone 2H7
Target Species Human
Applications FC
Supplier Thermo Fisher Scientific
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About CD20
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
About PE-eFluor 610
PE-eFluor™ 610 (PE-eF610, RPE-eF610) from Thermo Fisher Scientific is an orange-emitting tandem fluorophore that combines pycoerythrin (PE) and eFluor™ 610. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, eF610, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-eF610 has an excitation peak at 565 nm and an emission peak at 607 nm, and is suitable alternative to PE-Texas Red®. PE-eF610 is mainly used for flow cytometry. This tandem is often a great option because of PE is excitable by multiple lasers due to its broad excitation spectrum and the eFluor™ 610 acceptor molecule emits brightly in the Orange/Red spectrum. Many cytometers are commonly set up with the 610/20 bandpass filter that can detect this fluorophore's emission. This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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