CRTC1 / Unconjugated / A2-B5

Product Details
Description The TORC (transducer of regulated cAMP response element-binding) proteins, TORC1 and TORC2, are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner. The translocation of TORC proteins is a conserved step in the activation of CRE-mediated gene expression induced by cAMP. TORC1 and TORC2 operate via phosphorylation-dependent interactions.
Conjugate Unconjugated
Clone A2-B5
Target Species Human
Applications FC, ICC, WB
Supplier HuaBio
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About CRTC1
Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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