TRA-1-60 / PE / REA157
Product Details
Description | Clone REA157 recognizes the TRA-1-60 antigen, a neuraminidase-resistant carbohydrate epitope expressed on podocalyxin, which is a transmembrane glycoprotein. Podocalyxin is a member of the CD34-related family of sialomucins and is recognized as a stem cell and tumor marker. TRA-1-60 antigen is expressed on the surface of human embryonic stem cells (ESC), embryonic germ cells (EG), and embryonic carcinoma cells (EC). Expression of TRA-1-60 is lost upon differentiation and thus it can be used to assess the differentiation stage of the cells. TRA-1-60 can be detected in the serum of patients with germ cell tumors which contain an EC component. | Additional information: Clone REA157 displays negligible binding to Fc receptors. | | |
---|---|---|
Conjugate | PE | |
Clone | REA157 | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
Catalog # | Sign in to view product details, citations, and spectra | |
Size | ||
Price | ||
Antigen | ||
Host | ||
Isotype |
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
PMID 6396197 | |
---|---|
PMID 12115576 | |
PMID 17124010 | |
Additional Sources |
Reviews & Ratings
Reviews |
---|
Looking for more options?
45 TRA-1-60 antibodies from over 8 suppliers available with over 17 conjugates.