CLCA2 / Unconjugated / Polyclonal
Product Details
| Description | chloride channel accessory 2 | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | Polyclonal | |
| Target Species | Human | |
| Applications | ICC-IF, IHC | |
| Supplier | Atlas Antibodies | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CLCA2
This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. In breast cancer, expression of this gene is downregulated and the encoded protein may inhibit migration and invasion while promoting mesenchymal-to-epithelial transition in cancer cell lines. [provided by RefSeq, Sep 2016]
This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. In breast cancer, expression of this gene is downregulated and the encoded protein may inhibit migration and invasion while promoting mesenchymal-to-epithelial transition in cancer cell lines. [provided by RefSeq, Sep 2016]
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49 CLCA2 antibodies from over 10 suppliers available with over 12 conjugates.
