SPG21 / Unconjugated / Polyclonal
Product Details
| Description | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | Polyclonal | |
| Target Species | Human | |
| Applications | WB, IHC | |
| Supplier | Atlas Antibodies | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About SPG21
The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
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95 SPG21 antibodies from over 12 suppliers available with over 25 conjugates.
