GCLC / Unconjugated / Polyclonal
Product Details
| Description | glutamate-cysteine ligase, catalytic subunit | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | Polyclonal | |
| Target Species | Human | |
| Applications | WB, IHC | |
| Supplier | Atlas Antibodies | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About GCLC
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
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299 GCLC antibodies from over 16 suppliers available with over 42 conjugates.
