SP100 / Unconjugated / Polyclonal
Product Details
| Description | SP100 nuclear antigen | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | Polyclonal | |
| Target Species | Human | |
| Applications | ICC-IF, IHC | |
| Supplier | Atlas Antibodies | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About SP100
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]
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319 SP100 antibodies from over 14 suppliers available with over 37 conjugates.
