CD45 / redFluor 710 /

Product Details
Description CD45 (30-F11) Rat mAb (redFluorâ„¢ 710 Conjugate) recognizes endogenous levels of total mouse CD45 protein. This antibody detects an epitope within the extracellular domain.
Conjugate redFluor 710
Clone
Target Species Mouse
Applications FC
Supplier Cell Signaling Technology
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About CD45
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
About redFluor 710
redFluor 710 is a fluorophore with an excitation peak at 700 nm and an emission peak at 710 nm. It can be used with the following analysis platforms: Flow Cytometry.
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5460 CD45 antibodies from over 61 suppliers available with over 224 conjugates.

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