C-Myc / SureLight 488 /
Product Details
| Description | Mouse Anti-c-myc IgG conjugated to SureLight 488, 100ug not yet available | |
|---|---|---|
| Conjugate | SureLight 488 | |
| Clone | ||
| Target Species | ||
| Applications | FC | |
| Supplier | Columbia Biosciences | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About C-Myc
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
About SureLight 488
SureLight 488 from Columbia Biosciences is a fluorophore with an excitation peak at 496 nm and an emission peak at 517 nm. SureLight 488 is available in antibody conjugation kits for flow cytometry and fluorescence microscopy.
SureLight 488 from Columbia Biosciences is a fluorophore with an excitation peak at 496 nm and an emission peak at 517 nm. SureLight 488 is available in antibody conjugation kits for flow cytometry and fluorescence microscopy.
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