CD262 / Unconjugated / MD5-1

Product Details
Description InVivoMab anti-mouse DR5 (CD262), Clone: MD5-1, Size: 100 mg
Conjugate Unconjugated
Clone MD5-1
Target Species Mouse
Applications Activation
Supplier Bio X Cell
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About CD262
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
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