CD137 / VioBright FITC / 4B4-1
Product Details
| Description | This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4+ and CD8+ T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. | As a costimulatory molecule it is involved in the activation and survival of CD4+ or CD8+ T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8+ T cells, as it is not expressed on resting CD8+ T cells and its expression is reliably induced after 24 hours of stimulation. | |
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| Conjugate | VioBright FITC | |
| Clone | 4B4-1 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About VioBright FITC
Vio®Bright FITC has an excitation peak at 496 nm and an emission peak at 522 nm. It is recommended for use in flow cytometry and fluorescence microscopy.
Vio®Bright FITC has an excitation peak at 496 nm and an emission peak at 522 nm. It is recommended for use in flow cytometry and fluorescence microscopy.
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Validation References
| PMID 17371945 | |
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| PMID 16931626 | |
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