CD1c / APC-R700 / F10/21A3

Product Details
Description APC-R700 Mouse Anti-Human CD1c
Conjugate APC-R700
Clone F10/21A3
Target Species Human
Applications FC
Supplier BD Biosciences
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About CD1c
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
About APC-R700
APC-R700 from BD Biosciences has an excitation peak at 651 nm and an emission peak at 705 nm. It's useful in flow cytometry and is spectrally similar to APC-Cy5.5, APC-Alexa 700, APC-Alexa 680 and Seta-APC-705.
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