CD49f / SuperBright 600 / eBioGoH3 (GoH3)

Product Details
Description CD49f (Integrin alpha 6) Monoclonal Antibody (eBioGoH3 (GoH3)), Super Brightâ„¢ 600, eBioscienceâ„¢
Conjugate SuperBright 600
Clone eBioGoH3 (GoH3)
Target Species Human, Mouse
Applications FC
Supplier Thermo Fisher Scientific
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About CD49f
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
About SuperBright 600
SuperBright 600 (SB600) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 600 nm. SB600 is spectrally similar to StarBright Violet 610 and BV605. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
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