Aldehyde Dehydrogenase 3 / Unconjugated / OTI1B6

Product Details
Description ALDH3A1 Monoclonal Antibody (OTI1B6)
Conjugate Unconjugated
Clone OTI1B6
Target Species Human
Applications FC, IHC-P, WB, IHC
Supplier Thermo Fisher Scientific
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About Aldehyde Dehydrogenase 3
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
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