RB1 / Unconjugated /
Product Details
| Description | Rabbit polyclonal to RB1 | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Mouse | |
| Applications | WB | |
| Supplier | St John's Laboratory | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About RB1
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
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847 RB1 antibodies from over 18 suppliers available with over 51 conjugates.
