TIMP-2 / HRP / OTI1A6

Product Details
Description Mouse TIMP-2 antibody [HRP] detects Human, Mouse, Rat, Canine, Monkey
Conjugate HRP
Clone OTI1A6
Target Species Canine, Human, Monkey, Mouse, Rat
Applications WB, IHC
Supplier Novus Biologicals
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About TIMP-2
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
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