Sphingosine Kinase 1 / DyLight 755 / OTI1A6

Product Details
Description Mouse Sphingosine Kinase 1/SPHK1 antibody [DyLight 755] detects Human
Conjugate DyLight 755
Clone OTI1A6
Target Species Human
Applications ICC, IF, WB, IHC
Supplier Novus Biologicals
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About Sphingosine Kinase 1
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Phosphorylation of this protein alters its catalytic activity and promotes its translocation to the plasma membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2017]
About DyLight 755
DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
Experiment Design Tools
Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

414 Sphingosine Kinase 1 antibodies from over 23 suppliers available with over 41 conjugates.

Supplier Page
 Compare