RUNX1T1 / DyLight 488 / OTI1H1

Product Details
Description Mouse RUNX1T1/ETO antibody [DyLight 488] detects Human
Conjugate DyLight 488
Clone OTI1H1
Target Species Human
Applications ICC, IF, WB
Supplier Novus Biologicals
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About RUNX1T1
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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158 RUNX1T1 antibodies from over 16 suppliers available with over 32 conjugates.

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