MLPH / Unconjugated / OTI6E8

Product Details
Description Mouse Melanophilin antibody [Purified] detects Human
Conjugate Unconjugated
Clone OTI6E8
Target Species Human
Applications WB, IHC
Supplier Novus Biologicals
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About MLPH
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
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