IL-1 Receptor Antagonist / DyLight 405 / OTI2B1

Product Details
Description Mouse IL-1ra/IL-1F3/IL1RN antibody reacts with Human [DyLight 405]
Conjugate DyLight 405
Clone OTI2B1
Target Species Human
Applications WB, IHC
Supplier Novus Biologicals
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About IL-1 Receptor Antagonist
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]
About DyLight 405
DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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