Slan / PE / REA1050

Product Details
Description Clone REA1050 recognizes the human 6-sulfo LacNAc (Slan) (M-DC8) antigen, which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This antigen is characteristically expressed on a new subset of peripheral blood mononuclear cells (PBMCs) with features closely related to CD16+CD14low monocytes. Slan (M-DC8)+ cells constitute 0.5–2% of all PBMCs with similar frequencies among mononuclear cells from cord blood. | Additional information: Clone REA1050 displays negligible binding to Fc receptors.
Conjugate PE
Clone REA1050
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier Miltenyi Biotec
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About Slan
Enables RNA binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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44 Slan antibodies from over 5 suppliers available with over 25 conjugates.

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