MICA/MICB / Biotin / REA1076
Product Details
Description | Clone REA1076 recognizes MICA and MICB, which are transmembrane glycoproteins related to major histocompatibility complex (MHC) class I molecules. In contrast to other MHC class I proteins, MICA and MICB have no association with beta2-microglobulin and do not bind peptides. They are ligands for NKG2D, which is expressed on NK cells and many T cells. MICA and MICB are expressed on endothelial cells and fibroblasts and are stress-induced in epithelial cells. | Additional information: Clone REA1076 displays negligible binding to Fc receptors. | |
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Conjugate | Biotin | |
Clone | REA1076 | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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Validation References
PMID 2007850 | |
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PMID 10367903 | |
PMID 10426993 | |
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