IL-9 / Vio667 / REA1035

Product Details
Description Interleukin-9 (IL-9) is secreted by mast cells and T helper (Tʜ) cells. First IL-9 production was associated to Tʜ2 cells, but it was also found in other Tʜ subsets. Recently, evidence for the existence of a specialized lineage of Tʜ cells producing IL-9, named Tʜ9, came up. IL-9 has pleiotropic effects, e.g., it promotes mast cell growth and function, is involved in CD4+ T cell subset differentiation and growth, enhances IgE production, supports hematopoiesis, and acts on airway and gut epithelial cells. | Additional information: Clone REA1035 displays negligible binding to Fc receptors.
Conjugate Vio667
Clone REA1035
Target Species Mouse
Applications FC
Supplier Miltenyi Biotec
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About IL-9
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
About Vio667
Vio® 667 from Miltenyi has an excitation peak at 635 nm and an emission peak at 668. It is spectrally comparable to Cy5 and Alexa Fluor™ 647.
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