IgE / Biotin / MB10-5C4
Product Details
| Description | Anti-IgE antibodies react with the IgE isotype of human immunoglobulins. IgE is the shortest-lived immunoglobulin with a half-life of two days in serum. IgE plays an important role in allergy. It is especially associated with type 1 hypersensitivity, where IgE shows high-affinity binding to Fc receptors expressed on the surface of mast cells. Antigen binding to Fc receptor–bound IgE upon re-exposure to specific allergens results in degranulation and the release of a variety of mediators, such as histamine and cytokines. | IgE has two main receptors: the high-affinity receptor FcepsilonRI, which is expressed only on mast cells and basophils, and the low-affinity receptor FcepsilonRII (CD23), which is expressed on B cells. | | | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | MB10-5C4 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
| Size | ||
| Price | ||
| Antigen | ||
| Host | ||
| Isotype |
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
| Additional Sources |
|
|---|
Reviews & Ratings
| Reviews |
|---|
Looking for more options?
1004 IgE antibodies from over 31 suppliers available with over 77 conjugates.
