IFN-gamma / VioBlue / REA600

Product Details

Description	Clone REA600 recognizes the human interferon gamma (IFN-gamma) antigen, a cytokine of type II class interferons. IFN-gamma is produced by lymphocytes that are involved in inflammatory immune responses. It functions as a potent activator of macrophages, increases the antiviral and antitumor effects of the type I interferons, and has antiproliferative effects on transformed cells. IFN-gamma is predominantly released by memory and effector CD4+ and CD8+ T cells as well as by NK cells upon activation. \| Additional information: Clone REA600 displays negligible binding to Fc receptors.
Conjugate	VioBlue
Clone	REA600
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About IFN-gamma
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]

About VioBlue
Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).

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