CD93 / PE-Vio615 / REA1111
Product Details
| Description | Clone REA1111 recognizes the human CD93 antigen, also known as C1qRp, which is a 120 kDa heavily O-glycosylated protein. It is expressed on myeloid cells, platelets, endothelial cells, and immature dendritic cells whereas mature dendritic cells show weak to negative CD93 expression. C1qRp is involved in regulation of phagocytic activity, macrophage activation, and cell-cell adhesion. | Additional information: Clone REA1111 displays negligible binding to Fc receptors. | |
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| Conjugate | PE-Vio615 | |
| Clone | REA1111 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD93
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]
About PE-Vio615
PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594
PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594
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Validation References
| PMID 9469455 | |
|---|---|
| PMID 10092817 | |
| PMID 11781389 | |
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Reviews & Ratings
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