CD8 / VioBright 667 / REA734

Product Details
Description Clone REA734 recognizes the human CD8 antigen, a cell-surface glycoprotein also known as Leu-2 or CD8a. CD8 is strongly expressed on human cytotoxic T cells and thymocytes as well as on a subset of natural killer (NK) cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8a homodimer or as a CD8alpha/beta heterodimer. CD8 acts as a coreceptor for the T cell receptor and binds to the MHC class I molecules. CD8 is involved in T cell development and activation of mature T cells. The CD8 antibody recognizes the alpha-subunit of the antigen. | Additional information: Clone REA734 displays negligible binding to Fc receptors.
Conjugate VioBright 667
Clone REA734
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About VioBright 667
Vio®Bright® R667 from Miltenyi has an excitation peak at 635 nm and an emission peak at 668. It is spectrally comparable to Cy5 and Alexa Fluor™ 647 in flow cytometry.
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Validation References
PMID 9916707
PMID 11114424
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