CD71 / APC / REA627

Product Details

Description	Clone REA627 recognizes the mouse CD71 cell-surface antigen, which is also known as transferrin receptor protein 1 (TfR1), and essential for iron transport into proliferating cells. This homodimer is a single-pass type II membrane protein, which is able to bind one transferrin molecule per 90 kDa subunit. CD71 plays a role in cell proliferation by controlling the supply of iron and is expressed on erythroid precursors, immature proliferating cells, reticulocytes, but is very low expressed on resting leukocytes. \| Additional information: Clone REA627 displays negligible binding to Fc receptors.
Conjugate	APC
Clone	REA627
Target Species	Mouse
Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier	Miltenyi Biotec
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About CD71
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

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