CD49a / PE-Vio615 / REA1106

Product Details

Description	Clone REA1106 recognizes the cell adhesion molecule human CD49a, which is a 200 kDa heterodimeric integrin receptor. CD49a, also known as integrin alpha1, interacts with integrin beta1 (CD29) to form the VLA-1 complex which functions as a receptor for collagen and laminin-1. Integrin alpha1 plays a role in cell-cell adhesion and T cell proliferation and is expressed by activated T cells, NK cells, neuronal cells, fibroblasts, and mesenchymal cells. \| Additional information: Clone REA1106 displays negligible binding to Fc receptors.
Conjugate	PE-Vio615
Clone	REA1106
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About CD49a
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]

About PE-Vio615
PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594

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