CD326 / PE / caa7-9G8

Product Details
Description CD326 (EpCAM) is a 40 kDa transmembrane glycoprotein involved in cell adhesion, cell proliferation, and tumor progression. It functions as a homotypic calcium-independent cell adhesion molecule. CD326 is broadly expressed on epithelial cells including definitive endoderm cells, keratinocytes, immature thymocytes, langerhans cells, lymph node dendritic cells, thymic dendritic cells, splenic dendritic cells, and tumor cells including almost all carcinomas. Moreover, CD326 is expressed on mouse embryonic stem cells and was described as a marker for the identification of successfully reprogrammed induced pluripotent stem cells (iPS).
Conjugate PE
Clone caa7-9G8
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier Miltenyi Biotec
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About CD326
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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2467 CD326 antibodies from over 43 suppliers available with over 89 conjugates.

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