PTP epsilon / Unconjugated /

Product Details
Description PTPRE Antibody (OAAN02178) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse, Rat
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications WB, IHC
Supplier Aviva Systems Biology
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About PTP epsilon
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015]
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