Neurofilament Heavy 200kDa / Unconjugated / NF-05
Product Details
| Description | NEFH Antibody (OALA04232) Unconjugated Mouse Monoclonal Antibody, Reacts with Human, Rat, Pig | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | NF-05 | |
| Target Species | Human, Porcine, Rat | |
| Applications | ELISA, IHC-P, WB, IHC-Fr | |
| Supplier | Aviva Systems Biology | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Neurofilament Heavy 200kDa
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
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