Frizzled-3 / Unconjugated /
Product Details
Description | Frizzled-3 (FZD3) is a Frizzled Receptor that mediates Wnt signaling. It is widely expressed, mostly in brain and urogenital tissues. FZD3 is also expressed in the epidermis and developing hair follicles. FZD3 has been implicated in the development of axon tracts in the forebrain. A truncated form of FZD3 exists due to alternative splicing. | |
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Conjugate | Unconjugated | |
Clone | ||
Target Species | Porcine | |
Applications | IHC-P | |
Supplier | Aviva Systems Biology | |
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About Frizzled-3
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]
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