C5L2 / Unconjugated /

Product Details
Description GPR77 is an Anaphylatoxin Receptor. Binding to anaphylatoxins can result in increased triglyceride synthesis, although its precise role in cellular responses has not been determined.
Conjugate Unconjugated
Clone
Target Species Human
Applications IHC-P
Supplier Aviva Systems Biology
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About C5L2
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
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