T-bet / Unconjugated /

Product Details
Description TBX21 Antibody - C-terminal (OAPB01799) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications ELISA, IF, WB
Supplier Aviva Systems Biology
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About T-bet
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]
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