SNW1 / Unconjugated /

Product Details
Description SNW1 Antibody (OALA05245) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse, Rat
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications IHC-P, WB
Supplier Aviva Systems Biology
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About SNW1
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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