RNF7 / Unconjugated /
Product Details
| Description | RNF7 Antibody (OALA07124) Unconjugated Goat Polyclonal Antibody, Reacts with Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken, Xenopus, Zebrafish | |
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| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Bat, Bovine, Canine, Chicken, Equine, Gibbon, Gorilla, Human, Monkey, Mouse, Porcine, Rat, Zebrafish | |
| Applications | ELISA, IHC-P, WB | |
| Supplier | Aviva Systems Biology | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About RNF7
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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