STAT5 alpha / Unconjugated / 5F6.F1
Product Details
| Description | Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5a and Stat5. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus. | |
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| Conjugate | Unconjugated | |
| Clone | 5F6.F1 | |
| Target Species | Human, Mouse, Rat | |
| Applications | ELISA, WB, IHC | |
| Supplier | Aviva Systems Biology | |
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